Dr. Andrew Mackin, BVMS, MVS, DVS, DACVIM
Title:
- Head, Department of Clinical Sciences
Contacts:
ajm32@msstate.edu
Office: (662) 325-6631
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Overview
Summary:
Dr. Mackin is Professor and Head of the Department of Clinical Sciences. Dr. Mackin is a graduate of Murdoch University, and is an ACVIM Diplomate (Small Animal Internal Medicine).
Education:
- Doctor of Veterinary Science (D.V.S.), Veterinary Medicine, University of Guelph, 1994
- Master of Veterinary Science (MVS), Veterinary Medicine, University of Melbourne, 1988
- Bachelor of Veterinary Medicine and Surgery (BVMS), Veterinary Medicine, Murdoch University, 1983
- Bachelor of Science (B.S.), , Murdoch University, 1981
Research interests:
Clinical and research focus on hematology, hemostasis, immunosuppressive therapy and transfusion medicine.
Publications
Book, Chapter
- Immune-mediated haematological disease. Clinical Immunology of the Dog and Cat, Second Edition. 94-121. 2011
- Immune-mediated renal and reproductive disease. Clinical Immunology of the Dog and Cat, Second Edition. 251-262. 2011
- Platelet disorders. Consultations in Feline Internal Medicine. 575-584. 2006
Conference Proceeding
- Chronic management of the immune-mediated blood disorders. . Volume 48, Issue 2, Pages 46-49. 2018
- Practical blood transfusion in the dog and cat. . Volume 48, Issue 2, Pages 39-45. 2018
Journal Article
- Retrospective analysis of immunosuppressive and anti-thrombotic protocols in canine non-associative immune-mediated hemolytic anemia. J Vet Intern Med . Volume 37, Issue 2, Pages 528-536. 2023
- Effect of washing units of canine red blood cells on storage lesions. Journal of Veterinary Internal Medicine. Volume 36, Issue 1, Pages 66-77. 2022
- Effects of leukoreduction on N-methylhistamine concentration in stored units of canine whole blood. American journal of veterinary research. Volume 82, Issue 11, Pages 890-896. 2021
- Effects of Storage and Leukoreduction on N-Methylhistamine Concentrations in Units of Stored Canine Whole Blood. American Journal of Veterinary Research. Volume 82, Issue 11, Pages 890-896. 2021
- Anticoagulant profile of subcutaneous enoxaparin in healthy dogs. Journal of Veterinary Pharmacology and Therapeutics. Volume 00, Pages 1-12. 2021
- Effects of pentoxifylline on canine platelet aggregation. Veterinary Medicine and Science. Volume 7, Pages 2178-2184. 2021
- Efficacy of a low-dose praziquantel and fenbendazole protocol in the treatment of asymptomatic schistosomiasis in dogs. Journal of Veterinary Internal Medicine. Volume 35, Issue 3, Pages 1368-1375. 2021
- Nasal Rhinosporidiosis: Clinical Presentation, Clinical Findings, and Outcome in Dogs. Journal of the American Animal Hospital Association. Volume 57, Issue 3, Pages 114-120. 2021
- Mefenoxam, Itraconazole, and Terbinafine Combination Therapy for Management of Pythiosis in Dogs (Six Cases). Journal of the American Animal Hospital Association. Volume 56, Issue 6, Page 307. 2020
- Strategies to improve case outcome when referral is not affordable. Journal of Veterinary Medical Education. Volume 47, Issue 3, Pages 356-364. 2020
- Comparative repeatability of pancreatic lipase assays in the commercial and in-house laboratory environments.. Journal of veterinary internal medicine. 2020
- Excessive Cyclosporine-Associated Immunosuppression in a Dog Heterozygous for the MDR1 (ABCB1-1Δ) Mutation.. Journal of the American Animal Hospital Association. 2020
- Effects of oral administration of 5 immunosuppressive agents on activated T-cell cytokine expression in healthy dogs.. Journal of veterinary internal medicine. 2020
- Effects of pentoxifylline on whole blood IL-2 and IFN-gamma gene expression in normal dogs.. Veterinary medicine and science. Volume 6, Issue 1, Pages 19-24. 2020
- Effects of cyclosporine on feline lymphocytes activated in vitro. Veterinary Immunology and Immunopathology. Volume 219. 2020
- Recovery of T-cell function in healthy dogs following cessation of oral cyclosporine administration. Veterinary Medicine and Science. 2020
- Effects of cyclosporine and dexamethasone on canine T cell expression of interleukin-2 and interferon-gamma. Veterinary Immunology and Immunopathology. Volume 216. 2019
- What Is Your Diagnosis?. Journal of the American Veterinary Medical Association. Volume 255, Issue 7, Pages 785-788. 2019
- Assessment of erythrocyte damage and in-line pressure changes associated with simulated transfusion of canine blood through microaggregate filters.. American journal of veterinary research. Volume 80, Issue 9, Pages 852-861. 2019
- Coagulation factor activity in units of leukoreduced and nonleukoreduced canine fresh-frozen plasma. American Journal of Veterinary Research. Volume 80, Issue 9, Pages 846-851. 2019
- Alterations in activated T-cell cytokine expression in healthy dogs over the initial 7 days of twice daily dosing with oral cyclosporine. Journal of Veterinary Pharmacology and Therapeutics. Volume 42, Issue 4, Pages 385-391. 2019
- Technique for Evaluation of Gravity-Assisted Esophageal Transit Characteristics in Dogs with Megaesophagus. Journal of the American Animal Hospital Association. Volume 55, Issue 4, Pages 167-177. 2019
- Strategies to Improve Case Outcome When Referral Is Not Affordable.. Journal of veterinary medical education. Pages 1-9. 2019
- ACVIM consensus statement on the treatment of immune-mediated hemolytic anemia in dogs. Journal of Veterinary Internal Medicine. Volume 33, Issue 3, Pages 1141-1172. 2019
- Evaluation of a structured individualised protocol as a potential cost-effective diagnostic and therapeutic approach to chronic diarrhoea in the dog. Veterinary Medicine and Science. Volume 5, Issue 2, Pages 210-221. 2019
- Pharmacodynamic evaluation of the effects of oral melatonin on expression of the T-cell cytokines interleukin-2 and interferon gamma in the dog. Journal of Veterinary Pharmacology and Therapeutics. Volume 42, Issue 3, Pages 278-284. 2019
- Acute cerebrovascular event in a dog with polycythemia vera.. The Canadian veterinary journal = La revue veterinaire canadienne. Volume 59, Issue 7, Pages 755-758. 2018
- Effects of immunosuppressive agents on the hemostatic system in normal dogs. Journal of Veterinary Internal Medicine. Volume 32, Issue 4, Pages 1325-1333. 2018
- Bartonella henselae infection in a dog with recalcitrant ineffective erythropoiesis. Veterinary Clinical Pathology. Volume 47, Issue 1, Pages 45-50. 2018
- Evaluation of SNAP cPL, Spec cPL, VetScan cPL Rapid Test, and Precision PSL Assays for the Diagnosis of Clinical Pancreatitis in Dogs.. Journal of veterinary internal medicine. Volume 32, Issue 2, Pages 658-664. 2018
- In vivo effects of aspirin and cyclosporine on regulatory T cells and T-cell cytokine production in healthy dogs. Veterinary Immunology and Immunopathology. Volume 197, Pages 63-68. 2018
- Effects of aspirin dose escalation on platelet function and urinary thromboxane and prostacyclin levels in normal dogs. Journal of Veterinary Pharmacology and Therapeutics. Volume 41, Issue 1, Pages 60-67. 2018
- The effects of clopidogrel and omeprazole on platelet function in normal dogs. Journal of Veterinary Pharmacology and Therapeutics. Volume 40, Issue 2, Pages 130-139. 2017
- Effects of Leukoreduction and Storage on Erythrocyte Phosphatidylserine Expression and Eicosanoid Concentrations in Units of Canine Packed Red Blood Cells.. Journal of veterinary internal medicine. Volume 31, Issue 2, Pages 410-418. 2017
- Evaluation of eicosanoid concentrations in stored units of canine packed red blood cells.. Journal of the American Veterinary Medical Association. Volume 250, Issue 2, Pages 191-198. 2017
- Identification of histamine receptors in the canine gastrointestinal tract. Veterinary Immunology and Immunopathology. Volume 182, Pages 29-36. 2016
- The Effects of Cyclosporine and Aspirin on Platelet Function in Normal Dogs. Journal of veterinary internal medicine. Volume 30, Issue 4, Pages 1022-1030. 2016
- Effects of oral cyclosporine on canine T-cell expression of IL-2 and IFN-gamma across a 12-h dosing interval. Journal of Veterinary Pharmacology and Therapeutics. Volume 39, Issue 3, Pages 237-244. 2016
- Xenotransfusion of anemic cats with blood compatibility issues: pre- and posttransfusion laboratory diagnostic and crossmatching studies. Veterinary clinical pathology. Volume 45, Issue 2, Pages 244-253. 2016
- In vitro and in vivo assessment of platelet function in healthy dogs during administration of a low-dose aspirin regimen. American Journal of Veterinary Research. Volume 77, Issue 2, Pages 174-185. 2016
- Anticoagulant effects of inhaled unfractionated heparin in the dog as determined by partial thromboplastin time and factor Xa activity. Journal of Veterinary Emergency and Critical Care. Volume 26, Issue 1, Pages 132-136. 2016
- Evaluation of the effects of topical permethrin insecticide on bull semen quality Analytical validation of a quantitative reverse transcriptase polymerase chain reaction assay for evaluation of T-cell targeted immunosuppressive therapy in the dog. Clinical Theriogenology. Volume 6, Issue 3-4, Pages 25-31. 2014
- EFFECT OF LIPOSOMAL CLODRONATE-DEPENDENT DEPLETION OF PROFESSIONAL ANTIGEN PRESENTING CELLS ON NUMBERS AND PHENOTYPE OF CANINE CD4+CD25+FOXP3+ REGULATORY T CELLS.. Journal of veterinary medicine and research. Volume 1, Issue 1. 2014
- Pharmacokinetic evaluation of oral dantrolene in the dog. Journal of Veterinary Pharmacology and Therapeutics. Volume 37, Issue 3, Pages 286-294. 2014
- Evaluating the incidence of gastrocnemius tendon rupture in broiler chickens The effects of cyclosporine on platelet function and cyclooxygenase expression in normal dogs. International journal of poultry science. Volume 12, Issue 12, Pages 685-688. 2013
- Analytical validation of a quantitative reverse transcriptase polymerase chain reaction assay for evaluation of T-cell targeted immunosuppressive therapy in the dog. Veterinary Immunology and Immunopathology. Volume 156, Issue 3-4, Pages 229-234. 2013
- Cyclooxygenase Expression and Platelet Function in Healthy Dogs Receiving Low-Dose Aspirin. Journal of Veterinary Internal Medicine. Volume 27, Issue 1, Pages 141-149. 2013
- The Effects of Cyclosporine on Platelet Function and Cyclooxygenase Expression in Normal Dogs. Journal of Veterinary Internal Medicine. Volume 26, Issue 6, Pages 1389-1401. 2012
- Endoscopic placement of ureteral stents for treatment of congenital bilateral ureteral stenosis in a dog. Journal of the American Veterinary Medical Association. Volume 240, Issue 8, Pages 983-990. 2012
- Canine immune-mediated polyarthritis: PART 2: Diagnosis and treatment. Journal of the American Animal Hospital Association. Volume 48, Issue 2, Pages 71-82. 2012
- Effects of carprofen, meloxicam and deracoxib on platelet function in dogs. Veterinary Anaesthesia and Analgesia. Volume 39, Issue 2, Pages 206-217. 2012
- Pharmacodynamic Monitoring of Canine T-Cell Cytokine Responses to Oral Cyclosporine. Journal of Veterinary Internal Medicine. Volume 25, Issue 6, Pages 1391-1397. 2011
- Pharmacodynamic Monitoring of Canine T-Cell Cytokine Responses to Oral Cyclosporine. Journal of Veterinary Internal Medicine. Volume 25, Issue 6, Pages 1391-1397. 2011
- Platelet Cyclooxygenase Expression in Normal Dogs. Journal of Veterinary Internal Medicine. Volume 25, Issue 5, Pages 1106-1112. 2011
- Cyclosporine A affects the in vitro expression of T cell activation-related molecules and cytokines in dogs. Veterinary Immunology and Immunopathology. Volume 140, Issue 3-4, Pages 175-180. 2011
- Prevalence of and risk factors associated with shedding of Cryptosporidium felis in domestic cats of Mississippi and Alabama. Veterinary Parasitology. Volume 160, Issue 3-4, Pages 306-310. 2009
- Pharmacokinetics of subcutaneous low molecular weight heparin (enoxaparin) in dogs. Journal of the American Animal Hospital Association. Volume 45, Issue 6, Pages 261-267. 2009
- Pharmacokinetics of subcutaneous low molecular weight heparin (enoxaparin) in dogs. Journal of the American Animal Hospital Association. Volume 45, Issue 6, Pages 261-267. 2009
- Immune-mediated haemolytic anaemia in dogs - Therapy and prognosis. Magyar Allatorvosok Lapja. Volume 130, Issue 8, Pages 487-493. 2008
- Canine immune-mediated hemolytic anemia: Pathophysiology, clinical signs, and diagnosis. Compendium: Continuing Education For Veterinarians. Volume 29, Issue 4, Pages 217-225. 2007
- Canine immune-mediated hemolytic anemia: Treatment and prognosis. Compendium: Continuing Education For Veterinarians. Volume 29, Issue 4, Pages 230-239. 2007
- Genotypic analysis of Giardia duodenalis in domestic cats. Journal of Veterinary Internal Medicine. Volume 21, Issue 2, Pages 352-355. 2007
- In vivo recovery and survival of red cells after photodynamic treatment with thiopyrylium and red light using a canine model. Vox Sanguinis. Volume 92, Issue 2, Pages 157-159. 2007
- Prevalence and factors associated with fecal shedding of Giardia spp. in domestic cats.. Journal of the American Animal Hospital Association. Volume 42, Issue 6, Pages 424-9. 2006
- Tolerability and efficacy of benazepril in cats with chronic kidney disease. Journal of Veterinary Internal Medicine. Volume 20, Issue 5, Pages 1054-1064. 2006
- Comparison of the modified Seldinger and through-the-needle jugular catheter placement techniques in the dog. Journal of Veterinary Emergency and Critical Care. Volume 16, Issue 2, Pages 88-95. 2006
- Prevalence and factors associated with fecal shedding of Giardia spp. in domestic cats. Journal of the American Animal Hospital Association. Volume 42, Issue 6, Pages 424-429. 2006
- Diagnosing bleeding disorders. Compendium on Continuing Education for the Practicing Veterinarian. Volume 27, Issue 11, Pages 828-843. 2005
- Immune-mediated thrombocytopenia: Pathophysiology and diagnosis. Irish Veterinary Journal. Volume 58, Issue 11, Pages 637-639. 2005
- Nephrotic syndrome associated with administration of sulfadimethoxine/ ormetoprim in a dobermann. Journal of Small Animal Practice. Volume 46, Issue 5, Pages 232-236. 2005
- Relationship between red blood cell thiopurine methyltransferase activity and myelotoxicity in dogs receiving azathioprine. Journal of Veterinary Internal Medicine. Volume 18, Issue 3, Pages 339-345. 2004
- What is your diagnosis? A soft tissue opacity in the area of the pyloric antrum.. Journal of the American Veterinary Medical Association. Volume 224, Issue 5, Pages 665-6. 2004
- Humoral hypercalcemia of malignancy: Diagnosis and treatment. Compendium on Continuing Education for the Practicing Veterinarian. Volume 25, Issue 2, Pages 129-137. 2003
- Humoral hypercalcemia of malignancy: Pathophysiology and clinical signs. Compendium on Continuing Education for the Practicing Veterinarian. Volume 25, Issue 2, Pages 122-128. 2003
- Fluoroscopic and endoscopic localization of an esophagobronchial fistula in a dog. Journal of the American Animal Hospital Association. Volume 39, Issue 3, Pages 257-261. 2003
- What is your neurologic diagnosis? Nerve sheath tumor involving the brachial plexus with involvement of the spinal cord.. Journal of the American Veterinary Medical Association. Volume 221, Issue 10, Pages 1397-9. 2002
- What is your diagnosis? Spherical soft tissue opacity in the area of the distal portion of the trachea.. Journal of the American Veterinary Medical Association. Volume 221, Issue 6, Pages 783-4. 2002
- What is your diagnosis?. Journal of the American Veterinary Medical Association. Volume 221, Issue 1, Pages 37-38. 2002
- Evaluation of methods of platelet counting in the cat.. The Journal of small animal practice. Volume 42, Issue 7, Pages 326-32. 2001
- ECG of the month. Cardiac tamponade secondary to A. niger-induced constrictive pericarditis.. Journal of the American Veterinary Medical Association. Volume 218, Issue 12, Pages 1890-2. 2001
- Plasma vascular endothelial growth factor concentrations in healthy dogs and dogs with hemangiosarcoma.. Journal of veterinary internal medicine. Volume 15, Issue 2, Pages 131-5. 2001
- ECG of the month. Cardiac tamponade secondary to A. niger-induced constrictive pericarditis.. Journal of the American Veterinary Medical Association. Volume 218, Issue 12, Pages 1890-1892. 2001
- Idiopathic phenobarbital-responsive hypersialosis in the dog: an unusual form of limbic epilepsy?. The Journal of small animal practice. Volume 41, Issue 9, Pages 416-21. 2000
- Treatment of canine hemangiosarcoma: 2000 and beyond.. Journal of veterinary internal medicine. Volume 14, Issue 5, Pages 479-85. 2000
- Aetiology and diagnosis of persistent nasal disease in the dog: a retrospective study of 42 cases.. The Journal of small animal practice. Volume 40, Issue 10, Pages 473-8. 1999
- Measurement of titres of naturally occurring alloantibodies against feline blood group antigens in the UK.. The Journal of small animal practice. Volume 40, Issue 8, Pages 365-70. 1999
- Anesthesia case of the month. Cyanosis in a dog during anesthesia.. Journal of the American Veterinary Medical Association. Volume 214, Issue 7, Pages 1007-9. 1999
- Determination of the prevalence of feline blood types in the UK.. The Journal of small animal practice. Volume 40, Issue 3, Pages 115-8. 1999
- Primary immune-mediated thrombocytopenia in a cat.. The Journal of small animal practice. Volume 40, Issue 3, Pages 127-31. 1999
- Estimation of Platelet Counts on Feline Blood Smears. Veterinary Clinical Pathology. Volume 28, Issue 2, Pages 42-45. 1999
- Measurement of titres of naturally occurring alloantibodies against feline blood group antigens in the UK. Journal of Small Animal Practice. Volume 40, Issue 8, Pages 365-370. 1999
- Blood transfusions in the dog and cat Part 2: Indications and safe administration. In Practice. Volume 20, Issue 4, Pages 191-199. 1998
- Blood transfusions in the dog and cat: Part 1. Blood collection techniques. In Practice. Volume 20, Issue 3, Pages 110-114. 1998
- Development and Evaluation of an Endoscopic Technique Permitting Rapid Visualization of the Cardiac Region of the Porcine Stomach. Canadian Journal of Veterinary Research. Volume 61, Issue 2, Pages 121-127. 1997
- Concurrent hypoadrenocorticism and hypoalbuminemia in dogs: A retrospective study. Journal of the American Animal Hospital Association. Volume 31, Issue 4, Pages 307-311. 1995
- Effects of vincristine and prednisone on platelet numbers and function in clinically normal dogs. American Journal of Veterinary Research. Volume 56, Issue 1, Pages 100-108. 1995
- Exercise in electrocardiography.. The Canadian veterinary journal = La revue veterinaire canadienne. Volume 32, Issue 1, Pages 47-8. 1991
- Haemophilia A in a cocker spaniel dog.. Australian veterinary journal. Volume 65, Issue 10, Pages 326-7. 1988
Letter, Journal
- Treatment of immune-mediated polyarthritis in dogs. Journal of the American Veterinary Medical Association. Volume 248, Issue 8, Pages 876-877. 2016
- Serum Erythropoietin Assays: To the Editor. Journal of Veterinary Internal Medicine. Volume 8, Issue 4, Pages 314-315. 1994
Note, Journal
- What is your diagnosis?. Journal of the American Veterinary Medical Association. Volume 254, Issue 12, Pages 1393-1396. 2019
- Abnormalities of the thoracic bellows: stress fractures of the ribs and hiatal hernia.. Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. Volume 12, Issue 6, Pages 478-480. 1998
Review, Journal
- Anti-platelet therapy in small animal medicine. Journal of Veterinary Pharmacology and Therapeutics. Volume 39, Issue 4, Pages 318-335. 2016
- Oral cyclosporine treatment in dogs: A review of the literature. Journal of Veterinary Internal Medicine. Volume 28, Issue 1, Pages 1-20. 2014
- Canine immune-mediated polyarthritis. Journal of the American Animal Hospital Association. Volume 48, Issue 1, Pages 12-17. 2012
- Feline weight loss: Don't write off that thin old cat. Irish Veterinary Journal. Volume 61, Issue 1, Pages 40-44. 2008
- Immune-mediated hemolytic anemia in dogs; treatment and prognosis. Tierarztliche Praxis Ausgabe K: Kleintiere - Heimtiere. Volume 35, Issue 5, Pages 381-387. 2007
- Immune-mediated hemolytic anemia in the dog: Pathophysiology clinical symptoms and diagnosis. Tierarztliche Praxis Ausgabe K: Kleintiere - Heimtiere. Volume 35, Issue 4, Pages 302-308. 2007
- Thromboembolic Therapies in Dogs and Cats: An Evidence-Based Approach. Veterinary Clinics of North America - Small Animal Practice. Volume 37, Issue 3, Pages 579-609. 2007
- Lymphoid leukemia in dogs. Compendium on Continuing Education for the Practicing Veterinarian. Volume 28, Issue 12, Pages 831-849. 2006
- Approach to dysphagia and regurgitation. 2. Physical examination of patients with oesophageal disease. Irish Veterinary Journal. Volume 58, Issue 8, Pages 459-463. 2005
- Approach to dysphagia and regurgitation. Irish Veterinary Journal. Volume 58, Issue 7, Pages 400-407. 2005
- Immune-mediated haemolytic anaemia: Pathophysiology and diagnosis. Irish Veterinary Journal. Volume 58, Issue 6, Pages 345-349. 2005
- Challenging cases in internal medicine: What's your diagnosis?. Veterinary Medicine. Volume 96, Issue 3, Pages 206-215. 2001
Presentations
Lecture
- "Clinical Pathology: Respiratory collection, techniques and interpretation." Southern Veterinary Conference, , Birmingham Alabama. 2022
- "Cytology: Collection, processing and interpreting." Southern Veterinary Conference, , Birmingham Alabama. 2022
Oral Presentation
- "Erythrocyte damage and in-line pressure changes associated with transfusion of canine blood through microaggregate filters." American College of Veterinary Internal Medicine Forum, American College of Veterinary Internal Medicine, National Harbor, MD. 2017
Areas of Expertise
Small animal internal medicine hematology hemostasis transfusion medicine immunosuppressive therapy